Antibody Engineering
Structure and sequence-based design and optimization of antibodies targeted to your antigen
Structure Prediction
Predict Immunoprotein Structures
- Massively quick and scalable structure prediction for antibodies, TCRs, and nanobodies
- Antibody-antigen complex structure prediction
Design
Computationally design binders for your target
- Generate de-novo mini protein and antibody binders for a given antigen structure
- Redesign CDRs targeted to an antigen
- Produce point mutations for increased binding affinity and stability
Optimize
Improve multiple protein therapeutic propertiesSmooth look. Shiny creations.
- Optimize sequences for thermostability, solubility, and other developability properties
- Predict aggregation, immunogenicity, and developability for hundreds of thousands of sequences
- Integrate experimental data for higher scoring accuracy over rounds of designs
Docking
Dock protein-protein complexes at large scales
- Predict binding poses of antibody-antigen complexes
- Compute binding affinities using molecular dynamics and docking
